Table 2.
Structure of hPTG genes
Gene Name | Target Genes | # of gRNAs | Encoding gRNAs |
---|---|---|---|
hPTG1 | HDAC1 | 2 | HDAC1-sg1, HDAC1-sg2 |
hPTG2 | HDAC2 | 2 | HDAC2-sg1, HDAC2-sg2 |
hPTG3 | HDAC3 | 2 | HDAC2-sg1, HDAC2-sg2 |
hPTG4 | HDAC4 | 2 | HDAC4-sg1, HDAC4-sg2 |
hPTG5 | HDAC6 | 2 | HDAC6-sg1, HDAC6-sg2 |
hPTG6 | HDAC1, HDAC2, HDAC3 | 6 | HDAC1-sg1, HDAC1-sg2, HDAC2-sg1, HDAC2-sg2, HDAC2-sg1, HDAC2-sg2 |
hPTG7 | HDAC4, HDAC6 | 4 | HDAC1-sg1, HDAC1-sg2, HDAC6-sg1, HDAC6-sg2 |