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. 2017 Feb 1;8:27. doi: 10.3389/fimmu.2017.00027

Figure 4.

Figure 4

Augmented CD8+ T cell responses increase in the blood of Cyld−/− mice. (A,B) Absolute (A) and representative relative (B) numbers of CD3+ CD8+ T cells of uninfected (day 0) and Plasmodium berghei ANKA (PbA) blood stage-infected mice (day 7) were determined by flow cytometry in the blood of WT and Cyld−/− mice (n = 6 each), *p < 0.05 (two-tailed Student’s t-test). (C–F) Absolute (C) and representative relative numbers (E) of H2-Db SQLLNAKYL pentamer+ CD44+ CD8+ T cells. Absolute (D) and representative relative numbers (F) of interferon-γ-producing CD8+ T cells from uninfected (day 0) and PbA-infected mice at day 7 postinfection after ex vivo restimulation with GAP-50 peptide (n = 6 each), *p < 0.05 (two-tailed Student’s t-test). Data from one of three independent experiments are shown.