Table 1.
Characteristics of patients with cirrhosis enrolled in a pragmatic randomized controlled trial promoting HCC screening in safety-net system, overall and by study arm, December 2014 to March 2016, N = 1,800.
| Usual Care n=600 |
Outreach Alone n=600 |
Outreach and Patient Navigation n=600 |
Total N=1,800 |
|
|---|---|---|---|---|
|
| ||||
| Age (years) | ||||
| 21-50 | 183 (30.5) | 174 (29.0) | 158 (26.3) | 515 (28.6) |
| 51-60 | 259 (43.2) | 272 (45.3) | 269 (44.8) | 800 (44.4) |
| 61-90 | 158 (26.3) | 154 (25.7) | 173 (28.8) | 485 (26.9) |
|
| ||||
| Male sex (%) | 350 (58.3) | 361 (60.2) | 358 (59.7) | 1,069 (59.4) |
|
| ||||
| Race/Ethnicity (%) | ||||
| Non-Hispanic White | 182 (30.3) | 165 (27.5) | 163 (27.2) | 510 (28.3) |
| Hispanic | 217 (36.2) | 230 (38.3) | 234 (39.0) | 681 (37.8) |
| Non-Hispanic Black | 186 (31.0) | 197 (32.8) | 195 (32.5) | 578 (32.1) |
| Other/Unknown | 15 (2.5) | 8 (1.3) | 8 (1.3) | 31 (1.7) |
|
| ||||
| Etiology of Liver Disease (%)a | ||||
| Hepatitis C | 320 (53.3) | 285 (47.5) | 313 (52.2) | 918 (51.0) |
| Alcohol | 98 (16.3) | 115 (19.2) | 104 (17.3) | 317 (17.6) |
| NASH | 104 (17.3) | 101 (16.8) | 94 (15.7) | 299 (16.6) |
| Hepatitis B | 21 (3.5) | 27 (4.5) | 14 (2.3) | 62 (3.4) |
| Other | 57 (9.5) | 72 (12.0) | 75 (12.5) | 204 (11.3) |
|
| ||||
| Presence of documented cirrhosis (%)c | 472 (78.7) | 479 (79.8) | 482 (80.3) | 1,433 (79.6) |
|
| ||||
| Hepatic decompensation, No (%)a | 181 (30.2) | 192 (32.0) | 201 (33.5) | 574 (31.9) |
|
| ||||
| Child Pugh A (%)a | 432 (72.0) | 435 (72.5) | 424 (70.7) | 1,291 (71.7) |
|
| ||||
| Charlson Comorbidity Index (%)b | ||||
| 0 | 76 (12.7) | 95 (15.8) | 79 (13.2) | 250 (13.9) |
| 1 | 140 (23.3) | 143 (23.8) | 149 (24.8) | 432 (24.0) |
| 2 | 103 (17.2) | 99 (16.5) | 84 (14.0) | 286 (15.9) |
| 3+ | 281 (46.8) | 263 (43.8) | 288 (48.0) | 832 (46.2) |
|
| ||||
| Number of primary care visitsb | 4 (IQR 2-7) | 3 (IQR 2-7) | 4 (IQR 2-7) | 4 (IQR 2-7) |
|
| ||||
| Receipt of gastroenterology careb | 153 (25.5) | 153 (25.5) | 157 (26.2) | 463 (25.7) |
NASH = Nonalcoholic steatohepatitis; IQR – interquartile range
a
Prior to randomization
b
Within one year preceding randomization
c
Defined using ICD-9 codes for cirrhosis or cirrhosis-related complications