Table 2.

Frequency of funduscopic findings in each group

	Group 1	Group 2	Group 3	Overall P value*	P value†	P value‡	P value**
N. of participants	154	59	63
Drusen type
Small hard drusen	33.8 %	27.1 %	19.0 %	0.091
RPD	0.6 %	22.0 %	1.6 %	<0.001	0.497	<0.001	<0.001
Soft drusen	4.5 %	25.4 %	8.0 %	<0.001	0.110	<0.001	<0.001
Presence of DLD	24.7 %	3.4 %	9.5 %	<0.001	0.015	0.275	<0.001
Size of DLD				<0.001	0.001	1.000	0.002
<125 μm	80.5 %	96.6 %	96.8 %
> 125 μm	19.5 %	3.4 %	3.2 %
Pigmentary changes	39.6 %	35.6 %	14.3 %	0.001	<0.001	0.011	0.639

Group 1: fellow eye of unilateral polypoidal choroidal vasculopathy; Group 2: fellow eye of unilateral typical exudative age-related macular degeneration; Group 3: fellow eye of unilateral epiretinal membrane, as a control

Drusen-like deposits (DLD) were defined as sub-retinal or sub-retinal pigment epithelial grayish yellow deposits larger than 63 μm in size with irregular but discrete margins

RPD: reticular pseudodrusen

* comparison of all Groups; P value less than 0.05 is considered significant

^† comparison of Groups 1 and 3; P value less than 0.016 is considered significant

^‡ comparison of Groups 2 and 3; P value less than 0.016 is considered significant

^** comparison of Groups 1 and 2; P value less than 0.016 is considered significant