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. 2016 Sep 5;255(2):281–291. doi: 10.1007/s00417-016-3452-5

Table 2.

Frequency of funduscopic findings in each group

Group 1 Group 2 Group 3 Overall P value* P value P value P value**
N. of participants 154 59 63
Drusen type
 Small hard drusen 33.8 % 27.1 % 19.0 % 0.091
 RPD 0.6 % 22.0 % 1.6 % <0.001 0.497 <0.001 <0.001
 Soft drusen 4.5 % 25.4 % 8.0 % <0.001 0.110 <0.001 <0.001
Presence of DLD 24.7 % 3.4 % 9.5 % <0.001 0.015 0.275 <0.001
Size of DLD <0.001 0.001 1.000 0.002
<125 μm 80.5 % 96.6 % 96.8 %
> 125 μm 19.5 % 3.4 % 3.2 %
Pigmentary changes 39.6 % 35.6 % 14.3 % 0.001 <0.001 0.011 0.639

Group 1: fellow eye of unilateral polypoidal choroidal vasculopathy; Group 2: fellow eye of unilateral typical exudative age-related macular degeneration; Group 3: fellow eye of unilateral epiretinal membrane, as a control

Drusen-like deposits (DLD) were defined as sub-retinal or sub-retinal pigment epithelial grayish yellow deposits larger than 63 μm in size with irregular but discrete margins

RPD: reticular pseudodrusen

* comparison of all Groups; P value less than 0.05 is considered significant

comparison of Groups 1 and 3; P value less than 0.016 is considered significant

comparison of Groups 2 and 3; P value less than 0.016 is considered significant

** comparison of Groups 1 and 2; P value less than 0.016 is considered significant