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. 2016 Sep 5;255(2):281–291. doi: 10.1007/s00417-016-3452-5

Table 3.

Frequency of spectral domain optical coherence tomography findings in each group

Group 1 Group 2 Group 3 Overall P value* P value P value P value**
N. of participants 154 59 63
Double layer sign 9.1 % 10.2 % 0.0 % 0.015 0.012 0.011 0.797
Elevation by DLD or soft drusen 16.9 % 37.3 % 1.6 % <0.001 0.001 <0.001 0.003
Elevation by PED 5.8 % 8.5 % 0.0 % 0.049 0.062 0.024 0.539
Disruption of RPE 4.5 % 8.5 % 1.6 % 0.203
Choroidal thickness, μm 261.4 ± 99.0 178.2 ± 101.0 207.4 ± 77.6 <0.001 <0.001 0.080 <0.001

Group 1: fellow eye of unilateral polypoidal choroidal vasculopathy; Group 2: fellow eye of unilateral typical exudative age-related

macular degeneration; Group 3: fellow eye of unilateral epiretinal membrane, as a control

DLD, drusen-like deposits; PED, pigment epithelial detachment; RPE, retinal pigment epithelium

* comparison of all Groups; P value less than 0.05 is considered significant

comparison of Groups 1 and 3; P value less than 0.016 is considered significant

comparison of Groups 2 and 3; P value less than 0.016 is considered significant

** comparison of Groups 1 and 2; P value less than 0.016 is considered significant