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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Exp Neurol. 2016 Dec 28;289:85–95. doi: 10.1016/j.expneurol.2016.12.012

Figure 4.

Figure 4

Through the use of CTB conjugated to Alexa dyes to label retinogeniculate axon terminals, we find uniform labeling of ipsilateral and contralateral projecting axon terminals within both sides of dLGN (A). Images are adjusted for background fluorescence (B) before conversion to binary color scale images (C) for quantification of axon terminal reorganization. Examination of the percent of dLGN labeled by both ipsilateral and contralateral projecting axon terminals demonstrates a significant loss at 4 days post-injury which recovers at 10 days and 20 days post-injury. Examination of overlap between ipsilateral and contralateral projections demonstrates reorganization involves changes in the overlap between the two fiber populations however segregation is maintained relative to sham condition. Error bars derived from standard deviation. Asterisk over bars indicate comparison p value is < 0.05, n.s. = no significance.