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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Differentiation. 2016 Dec 3;93:58–65. doi: 10.1016/j.diff.2016.11.003

Fig.4. Cell lineage studies.

Fig.4

A. Evidence that induced cardiomyocytes are derived from satellite cells. Pax7 expressing cells were labeled by treating the Pax7-CreER;mT/mG mice with tamoxifen. The green label indicates that cTnT-positive cardiomyocytes formerly expressed Pax7. Scale bar 25μm. B. Evidence that induced cardiomyocytes are derived from the secondary heart field. Satellite cells were prepared from Isl1-Cre;mTmG mice and then sorted for GFP expression, and subjected to the cardiomyocyte differentiation procedure. The NKX2.5 and cTnT-positive cells must be derived from cells that had expressed Isl1 in vivo. Scale bar: 25μm.