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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Pharm Res. 2016 Dec 13;34(3):544–551. doi: 10.1007/s11095-016-2086-y

Figure 2. Predictions of Vss.

Figure 2

Predicted versus observed Vss are plotted with A) experimental fum or B) fum predicted with equation 1. See drug list (n=63) in Table S2. Red: acidic drugs, blue: basic drugs, green: neutral drugs. Open circles represent outliers. The dashed and dotted lines represent 2-fold and 3-fold error, respectively. R2 values including and excluding outliers are listed.