Table 4.
Cost analysis for device production of microfluidic and nanofluidic devices using a “Cost of Goods” analysis. Please note that these production costs do not include overhead charges or research & business development costs.
| Item | Microfluidics | Nanofluidics |
|
| Cost/4” chip [$] | Cost/4” chip [$] | ||
| Master Mold1 | 0.10 | 3.00 | |
| Molding2 | 0.20 | 0.40 | |
| Post-processing3 | 0.25 | 0.25 | |
| Polymer substrate | 0.25 (PMMA) | 0.25 (PMMA) | |
| Assembly4 | 1.05 | 3.20 | |
| Chemicals | 0.20 | 0.50 | |
| Biologics | 1.00 | 1.00 | |
| Electronic Connects | 0.85 | 3.55 | |
| Labor | 1.10 | 2.50 | |
| Total cost per chip | 5.00 | 14.65 | |
| Production Rate5 | 150/day (8 hrs) | 150/day (8 hrs) |
1
Amortization for 1,000 imprinting from single master and 20 polymer stamps.
2
Includes equipment amortization.
3
Cleaning of chip and activation for biologic attachment.
4
Includes cover plate material, equipment amortization for assembly.
5
The production rate is limited in both cases by the cycle time for the imprinting step for a single machine. Use of roll-to-roll imprinting will increase this production rate.