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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Adv Drug Deliv Rev. 2016 Nov 14;108:68–82. doi: 10.1016/j.addr.2016.11.001

Figure 3.

Figure 3

Compressive elastomeric systems. (a) Reduction of blood glucose in rats with the release of insulin from silicone implants upon stimulation every 2 days. (b) Schematic representation of release when compression of the device reaches the critical strain (εc). Release profile of rhodamine B with three bending events with bending radius of (c) 45 mm, and (d) 19 mm. (d) Modulation of release with channel volume. Figures are reprinted with permission from Refs. [99] and [101].