Table 1. Clinical variables and laboratory values during the course of the patient's illnessa.
| Clinical and laboratory findings | Day7b | Day 8 | Day 9 | Day 10 | Day 11 | Day 12 | Day 13 | Day 17 | Day 20 | Day 29 | Normal range |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Clinical variables | |||||||||||
| Temperature (°C) | 37.0 | 36.8 | 36.7 | 37.2 | 36.9 | 36.7 | 37.8 | 37.7 | 38.0 | 37.0 | 36–37 |
| Mean artery blood pressure (mm Hg) | 77 | 81 | 89 | 103 | 82 | 102 | 105 | 110 | 97 | 94 | 70–105 |
| Urinary output (mL/24 h) | 0 | 0 | 0 | 200 | 300 | 500 | 500 | 1800 | 3500 | 2800 | 1500–2500 |
| Laboratory values | |||||||||||
| WBC ( × 109/L) | 6.77 | 5.91 | 8.19 | 8.61 | 9.09 | 7.07 | 6.54 | 6.27 | 6.97 | 6.85 | 4.00–10.00 |
| Neutrophils ( × 109/L) | 4.84 | 4.53 | 5.93 | 6.06 | 6.20 | 4.53 | 4.19 | 4.28 | 4.50 | 5.10 | 2.00–8.00 |
| Platelets ( × 109/L) | 99 | 104 | 70 | 79.4 | 85.4 | 63 | 54 | 129 | 202 | 280 | 100–300 |
| Haemoglobin (g/L) | 155.4 | 137.4 | 129.4 | 130.4 | 129.0 | 130.0 | 115.0 | 97.0 | 77.0 | 75.0 | 120.0–160.0 |
| ALT (U/L) | 5910 | 5394 | 3052 | 1968 | 857 | 622 | 398 | — | 67 | 194 | 9–50 |
| AST (U/L) | 7570 | 6180 | 1819 | 612 | 125 | 70 | 87 | — | 46 | 90 | 15–40 |
| TBIL (μmol/L) | 83.8 | 87.3 | 87.4 | 59.7 | 46.1 | 45.0 | 68.2 | — | 19.0 | 16.6 | 0–18.8 |
| DBIL (μmol/L) | 71.8 | 73.4 | 75.9 | 52.4 | 37.6 | 37.7 | 55.3 | — | 14.4 | 11.1 | 0–6.8 |
| LDH (U/L) | 1880 | 2754 | 1580 | 807 | 523 | — | 362 | — | — | — | 80–285 |
| MYO (ng/mL) | 1200 | 1020 | — | — | 197 | 102 | — | — | — | — | 0–140 |
| CK (U/L) | 6680 | 6332 | — | 819 | 74 | — | 44 | — | — | — | 38–174 |
| CK-Mb (U/L) | 86 | 77 | — | 26 | 15 | — | 7 | — | — | — | <25 |
| Creatinine (μmol/L) | 1005 | 1097 | 540 | 275 | 217 | 274 | 244 | 338 | 233 | 139 | 59–104 |
| BUN (mmol/L) | 35.2 | 37.9 | 19.7 | 10.4 | 10.6 | 13.0 | 10.9 | 8.7 | 16.6 | 8.0 | 1.7–8.3 |
| PT (s) | 14.0 | 14.1 | 10.3 | 10.3 | 10.7 | 10.8 | 12.0 | 11.3 | — | 10.2 | 9.4–12.5 |
| AMY (U/L) | 132 | — | 284 | 275 | 192 | — | — | — | — | — | 35–135 |
| LPS (U/L) | 58.0 | — | 468.0 | 341.0 | 67.0 | — | — | — | — | — | 5.6–51.0 |
| CRP (mg/L) | 18.5 | 17.7 | — | — | 16.1 | 28.5 | — | — | — | 0–5.0 | |
| PCT (ng/mL) | 71.80 | — | — | — | — | — | — | 6.80 | — | — | <0.05 |
Abbreviations: alanine aminotransferase, ALT; amylase, AMY; aspartate aminotransferase, AST; blood urea nitrogen, BUN; creatine kinase, CK; C-reactive protein, CRP; direct bilirubin, DBIL; lactate dehydrogenase, LDH; lipase, LPS; myohaemoglobin, MYO; procalcitonin, PCT; prothrombin time, PT; total bilirubin, TBIL; white blood cell, WBC.
a
Unavailable information for the tests is denoted as '—'.
b
Days after disease onset.