Table 2.
Increase in IsoPs between 14 and 28 days is associated with worse neurodevelopmental scores at 12 months of corrected age
| Outcome | Model | OR | 95% Cl | P-value | 
|---|---|---|---|---|
| (a) ORs for higher scores per 50-unit increase in IsoP | ||||
| Cognition | Unadjusted | 0.74 | (0.62 to 0.88) | <0.001 | 
| Communication | Unadjusted | 0.81 | (0.69 to 0.95) | 0.010 | 
| Motor | Unadjusted | 0.75 | (0.64 to 0.88) | <0.001 | 
| Cognition | Adjusted | 0.72 | (0.59 to 0.88) | 0.001 | 
| Communication | Adjusted | 0.81 | (0.68 to 0.97) | 0.026 | 
| Motor | Adjusted | 0.69 | (0.57 to 0.84) | <0.001 | 
| Outcome | Model | Score change in points | Cl | P-value | 
|  | ||||
| (b) Predicted change in DAYC scores per 50-unit increase in IsoP | ||||
| Cognition | Unadjusted | − 1.81 | (−2.77 to − 0.85) | <0.001 | 
| Communication | Unadjusted | − 1.05 | (−1.93 to − 0.16) | 0.010 | 
| Motor | Unadjusted | − 2.18 | (−3.20 to − 1.17) | <0.001 | 
| Cognition | Adjusted | − 1.87 | (−2.95 to − 0.79) | 0.001 | 
| Communication | Adjusted | − 1.05 | (−1.05 to − 0.07) | 0.026 | 
| Motor | Adjusted | − 2.30 | (−3.43 to − 1.17) | <0.001 | 
Abbreviations: CI, confidence interval; DAYC, Developmental Assessment of Young Children; IsoP, F2-isoprostane; OR, odds ratio.