Table 2.
Synaptic properties for climbing fibres recorded from Purkinje cells in weanling (P21–24) mice
| Condition | |||
|---|---|---|---|
| Weanling (P21–24) Purkinje cell synaptic properties | WT | SCA684Q/84Q | P |
| CF‐EPSC rise time (ms) | 0.42 ± 0.004 | 0.42 ± 0.003 | 0.80 |
| CF‐EPSC τ decay (ms) | 10.32 ± 0.05 | 10.33 ± 0.04 | 0.92 |
| CF max. amplitude (nA) | 1.85 ± 0.08 | 1.92 ± 0.07 | 0.54 |
| CF disparity index | 1.35 ± 0.02 | 1.36 ± 0.01 | 0.68 |
| CF disparity ratio | 0.058 ± 0.020 | 0.044 ± 0.010 | 0.56 |
| n for CF data (subset of cells analysed for disparity)a | 25 (7) | 27 (8) | |
Mean ± SEM is shown for each condition, and the P value for a Student's t test comparison is shown. aOnly the subset of multiply‐innervated climbing fibres can be analysed for the Disparity index and ratio, and the n for this analysis is indicated in the parentheses.