Table 5.
Linear ERR per Gy and 90% confidence intervals (CI) by age at exposure (AE) and time since exposure (TSE).1,2
| Outcome | AE (years) | TSE (years) | Heterogeneity (LRT p-value, 8 df)3 | ||
|---|---|---|---|---|---|
|
| |||||
| 2<10 | 10<20 | 20+ | |||
| All solid cancers | <35 | -0.88 (NC, 6.53) | 0.54 (-2.27, 4.14) | -0.77 (-1.56, 0.11) | 0.682 |
| 35<50 | 1.25 (-1.26, 4.23) | 0.74 (-0.60, 2.20) | 0.75 (0.03, 1.42) | ||
| 50+ | 0.01 (-1.44, 1.61) | 0.74 (-0.30, 1.91) | 0.27 (-0.75, 1.44) | ||
|
| |||||
| Leukemia excl. CLL | <35 | 16.56 (NC, 52.6) | 8.11 (NC, 35.86) | 2.86 (-3.42, 11.44) | 0.064 |
| 35<50 | 0.93 (NC, 11.19) | -13.09 (NC, -2.0) | 5.11 (0.07, 11.37) | ||
| 50+ | -6.66 (-10.69, 3.16) | 6.65 (-2.96, 20.72) | 8.75 (1.04, 20.66) | ||
1
Extrapolating estimates to 1Gy resulted in artefactual values (i.e., ERR per Gy <-1) for some outcomes. These estimates are shown for completeness only.
2
Profile-likelihood confidence intervals calculated with 1 df.
3
Compared to a model where all parameters are equal.
Abbreviations: AE, age at exposure; CI, confidence interval; CLL, chronic lymphocytic leukemia; df, degrees of freedom; ERR, excess relative risk; LRT, likelihood ratio test; NC, not calculable; TSE, time since exposure.