Skip to main content
. 2016 Dec 22;9(2):181–197. doi: 10.15252/emmm.201606684

Figure EV5. Huwe1‐deficient tumours display Apc LOH.

Figure EV5

  1. Quantification of γ‐H2AX IHC demonstrating increased number of nuclei staining positive following Huwe1 deletion (Mann–Whitney, n = 3 versus 4). Data plotted are mean and SD.
  2. Apc LOH PCR analysis of tumours isolated from Vil Apc, Vil Apc Huwe1 het and Vil Apc Huwe1 hom mice. The majority of tumours display Apc LOH.