Figure EV6. MCL1 protects Huwe1‐deficient tumours from apoptosis.

1. Quantification of scoring of apoptotic bodies in control, Mcl1^fl/+, Huwe1^fl/fl and Huwe1^fl/fl Mcl^1fl/+ deleted intestines (Mann‐Whitney, P = 0.0259, n = 3 vs 4). Data are mean and SD.
2. Classification of adenoma and indolent lesions observed in Lgr5 Apc Huwe1 (left panel) and Lgr5 Apc Huwe1 Mcl1^het (right panel) mice. Scale bars = 100 μm.
3. Image of intestines from Lgr5 Apc Huwe1 (left panel) and Lgr5 Apc Huwe1 Mcl1^het (right panel) mice. Adenomas indicated by red arrows and indolent lesions by black arrows. Note the decreased ration of adenomas/indolent lesions observed in Mcl1^het intestines. Scale bars = 100 μm.