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. 2017 Feb 1;7:41868. doi: 10.1038/srep41868

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Genes overexpressed in this study are indicated in green and genes deleted are indicated in red. Abbreviations: VLCFA, very-long-chain fatty acid (C₂₄-C₂₆); LCB, long-chain base; PI, phosphatidylinositol; PI4P, phosphatidylinositol 4-phosphate; IPC, inositol phosphoceramide; MIPC, mannosyl-inositol phosphoceramide; MIP2C, mannosyl-diinositolphosphoceramide. The Illustration is drawn by the authors.