Figure 3. Cellular uptake of retinoids and transporter modulators.

Samples containing retinoids or transporter inhibitors were incubated with NIH 3T3 cells (1 × 10⁶/ml) for 30 min at 37 °C, then the cells were removed by 5 min centrifugation at 400 × g. Cellular uptake of the examined compounds was determined by calculating the ratio of the absorbances measured in the supernatants before and after incubation with cells. (n = 3, mean ± SD).