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. 2017 Feb 1;7:38232. doi: 10.1038/srep38232

Figure 1. miR-34a inhibits pancreatic cancer cell migration and invasion and induces apoptosis.

Figure 1

(A) RT-PCR results demonstrate that the expression levels of miR-34a were significantly lower in pancreatic cancer cell lines PANC-1 and SW-1990 than normal HPDEC. (B) Changes in miR-34a levels in the cell lines 24 h after transfection with the vehicle, the miR-34a mimics, the mimic control, the miR-34a inhibitors or the inhibitor control. (C) Following 24 h transfection of pancreatic cancer cell lines with miR-34a mimics or inhibitors, cells were stained with FITC Annexin V and PI for FC analysis. (D) Cell migration assays were performed. (E) Cells invasion assays were performed. Con control, M the miR-34a mimics, I the miR-34a inhibitors.*p < 0.05.