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. 2017 Feb 1;7:38232. doi: 10.1038/srep38232

Figure 2. Snail1 is a target gene of miR-34a.

Figure 2

(A,B) Forty-eight hours after transfection with miR-34a mimics or inhibitors in pancreatic cancer cell lines, the protein levels of Snail1, E-cadherin and N-cadherin in the cells were measured. (C) The miR-34a binding sites in the 3′-UTR of the Snail1 gene. (D) The wild type and mutant binding sites for miR-34a in the 3′-UTR of the Snail1 gene. (E) The relative luciferase activity. Con control, M the miR-34a mimics, I the miR-34a inhibitors, MC mimic control, IC inhibitor control, wt wild type, mut mutant type. *p < 0.05. The full length blots are presented in Supplementary Figs S1 and S2.