Table 2.

Corneal wavefront aberrations before and 1, 6, 12, and 24 months after accelerated corneal cross-linking.

Characteristics (mean ± SD)	Preoperative	1 M	6 M	12 M	p 1	24 M	p 2
Total WFE	1.36 ± 0.59	1.38 ± 0.56	1.34 ± 0.56	1.37 ± 0.54	0.986	1.30 ± 0.56	0.116
Total HOA	0.54 ± 0.26	0.53 ± 0.25	0.51 ± 0.28	0.50 ± 0.25	0.001∗	0.50 ± 0.26	0.001∗
Astigmatism	1.23 ± 0.57	1.25 ± 0.55	1.21 ± 0.53	1.25 ± 0.56	0.582	1.18 ± 0.55	0.073
Trefoil	0.17 ± 0.10	0.17 ± 0.10	0.17 ± 0.10	0.16 ± 0.09	0.505	0.16 ± 0.11	0.459
Coma	0.45 ± 0.26	0.45 ± 0.25	0.43 ± 0.26	0.42 ± 0.25	0.009∗	0.42 ± 0.25	0.007∗
Quadrafoil	0.05 ± 0.03	0.06 ± 0.05	0.06 ± 0.03	0.06 ± 0.04	0.406	0.06 ± 0.04	0.237
Secondary astigmatism	0.08 ± 0.05	0.07 ± 0.04	0.07 ± 0.06	0.06 ± 0.05	0.062	0.07 ± 0.05	0.072
Spherical aberration	0.08 ± 0.06	0.08 ± 0.06	0.07 ± 0.06	0.07 ± 0.07	0.084	0.07 ± 0.06	0.060

SD: standard deviation, M: month, WFE: wavefront error, HOA: high order aberrations, p ¹, comparison of preoperative and 12th month values, p ², comparison of preoperative and 24th month values, and ^∗statistically significant increased values (p < 0.05).