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. 2017 Feb 1;7:41261. doi: 10.1038/srep41261

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Framework for atlas comparison for two subpopulations, C⁺ and C⁻; (1) Statistical shape atlases are constructed for (a) C⁺ and (b) C⁻ for the entire prostate (grey, purple) and CG (red, purple); (2) The C⁺ and C⁻ atlases are aligned to a common space; (3) per-voxel statistical comparisons are performed to assess shape differences on the prostate boundary and CG.