Table 2. Whole genome sequencing statistics for the family.

Family member	#of reads	#of variants	#rare variants (MAF <0.01)	Average coverage
II-2	1,294,717,932	3,884,626	1,019,066	64.74
II-3	604,579,332	3,643,750	921,560	30.23
II-1	1,271,485,728	3,850,633	1,017,205	63.57
I-2	706,084,970	3,819,074	982,427	35.30
I-1	650,834,656	3,826,470	996,484	32.54

MAF, minor allele frequency.