(A) Biosynthesis of L-2,3-diaminopropionic acid (Dap). (B) Structure of nocardicin G, the first β-lactam containing intermediate in the pathway to nocardicin A. (C) Alternative possible biosynthetic routes to sulfazecin.
PAPS, 3′-phosphoadenosine-5′-phosphosulfate; SAM, S-adenosyl methionine; TE, thioesterase; α-KG, α-ketoglutaric acid; L-phosphoSer, L-phosphoserine.