Table 1.
Statistical analysis.
| Line | Data structure | Type of test | Power |
|---|---|---|---|
| a | Normal distribution | Two-way repeated-measures ANOVA (repeated factor: time; other factor: treatment) followed by Holm–Sidak test | For treatment: 0.944 For time: 1.000 For interaction: 0.669 |
| b | Normal distribution | One-way repeated-measures ANOVA (repeated factor: time) | Too small to calculate |
| c | Normal distribution | Two-way repeated-measures ANOVA (repeated factor: time; other factor: treatment) followed by Holm–Sidak test | For treatment: 0.458 For time: 1.000 For interaction: 0.598 |
| d | Normal distribution | Two-way repeated-measures ANOVA (repeated factor: time; other factor: treatment) followed by Holm–Sidak test | For treatment: 0.0734 For time: 0.999 For interaction: 0.349 |
| e | Normal distribution | Welch’s t-test | Four hour 95% CI: 2.7–3.5 mm Four day 95% CI: 3.2–3.9 mm Two week 95% CI: 3.4–4.5 mm |
| f | Normal distribution | Two-way repeated-measures ANOVA (repeated factor: time; other factor: treatment) followed by Holm–Sidak test | For treatment: 0.998 For time: 1.000 For interaction: 0.980 |
| g | Normal distribution | Two-way repeated-measures ANOVA (repeated factor: time; other factor: treatment) followed by Holm–Sidak test | For treatment: 0.856 For time: 1.000 For interaction: 0.959 |
| h | Normal distribution | Two-way repeated-measures ANOVA (repeated factor: time; other factor: treatment) followed by Holm–Sidak test | For treatment: 0.846 For time: 1.000 For interaction: 0.691 |
| i | Normal distribution | Two-way repeated-measures ANOVA (repeated factor: time; other factor: treatment) followed by Holm-Sidak test | For treatment: 0.725 For time: 1.000 For interaction: 0.880 |
| j | Normal distribution | Two-way repeated-measures ANOVA (repeated factor: time; other factor: treatment) followed by Holm–Sidak test | For treatment: 0.202 For time: 1.000 For interaction: 0.501 |
| k | Normal distribution | Two-way repeated-measures ANOVA (repeated factor: time; other factor: treatment) followed by Holm–Sidak test | For treatment: 0.115 For time: 0.961 For interaction: Too small to calculate |
| l | Normal distribution | Two-way repeated-measures ANOVA (repeated factor: time; other factor: treatment) followed by Holm–Sidak test | For treatment: 0.804 For time: 1.000 For interaction: 0.250 |
| m | Normal distribution | Two-way repeated-measures ANOVA (repeated factor: time; other factor: treatment) followed by Holm–Sidak test | For treatment: 0.250 For time: 1.000 For interaction: 0.363 |
| n | Normal distribution | Two-way repeated-measures ANOVA (repeated factor: time; other factor: treatment) followed by Holm–Sidak test | For treatment: 0.456 For time: 1.000 For interaction: 0.129 |
| o | Normal distribution | Two-way repeated-measures ANOVA (repeated factor: time; other factor: treatment) followed by Holm–Sidak test | For treatment: 0.318 For time: 0.892 For interaction: 0.194 |
| p | Normal distribution | Two-way repeated-measures ANOVA (repeated factor: time; other factor: treatment) followed by Holm–Sidak test | For treatment: too small to calculate For time: 1.000 For interaction: too small to calculate |
| q | Normal distribution | Two-way repeated-measures ANOVA (repeated factor: time; other factor: treatment) followed by Holm–Sidak test | For treatment: too small to calculate For time: 0.730 For interaction: too small to calculate |
| r | Normal distribution | Two-way ANOVA (factors: time, treatment) | For treatment: 0.050 For time: 0.195 For interaction: 0.050 |
| s | Normal distribution | Two-way ANOVA (factors: time, treatment) | For treatment: 0.050 For time: 0.050 For interaction: 0.050 |
| t | Normal distribution | Welch’s t-test | Four hour 95% CI: 3.9–4.2 mm Four day 95% CI: 3.4–4.4 mm Two week 95% CI: 3.1–3.8 mm |
CI, confidence interval.