Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Feb 1;16:27. doi: 10.1186/s12943-017-0606-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 3 — p38 and p42/44 MAPK signaling pathways regulate IL1-mediated OPG secretion in breast cancer cells. a Relative OPG mRNA and b OPG secreted protein levels measured 24 h after the simultaneous treatment of IL1B (10 ng/mL) and MAPK inhibitor(s) (10 μM) of p38 (SB202190, SB203580), p42/44 (U0126, BAY869766), and JNK (SP600125)) (n ≥ 3) in BT549, ZR75-1 and SKBR3 breast cancer cell lines. Data are represented by mean ± SD. ^ denotes p < 0.05, as compared to DMSO; asterisks denotes p < 0.05, as compared to DMSO + IL1B