Table 2.
Characteristics of T2DM subjects according to thyroid autoimmunity status
| Variable | Positive Thyroid autoimmunity | Negative thyroid autoimmunity | P |
|---|---|---|---|
| Number (%) | 64 (21.2) | 239 (78.8) | <0.0001 |
| Female Gender, n (%) | 58 (70) | 138 (57.7) | 0.04 |
| Age, years, (mean ± SD) | 57.5 ± 9.0 | 57.4 ± 9.5 | 0.93 |
| Duration of T2DM, median (IQR) | 5 (3–10) | 5 (2–10) | 0.49 |
| Systolic blood pressure, median (IQR) | 140 (130–160) | 139 (130–150) | 0.33 |
| Diastolic blood pressure, median (IQR) | 85.5 (70–90) | 80 (72–90) | 0.31 |
| Smoking, n (%) | 7 (13.0) | 15 (6.3) | 0.27 |
| Alcohol, n (%) | 31 (48.4) | 86 (36.0) | 0.08 |
| BMI, Kg/m2, median (IQR) | 24.7 (24.8–30.4) | 26.9 (24.5–32.1) | 0.79 |
| Waist circumference, cm, median (IQR) | 99 (88–109) | 95 (86–102) | 0.04 |
| Fasting blood glucose, mmol/L, median (IQR) | 9.7 (8.7–11.2) | 7.6 (6.7–9.4) | <0.0001 |
| HbA1c % median IQR | 8.2 (6.8–9.8) | 6.1 (5.2–9.6) | <0.001 |
| TC median IQR | 6.03 (4.7–7.06) | 4.9 (3.9–5.7) | <0.001 |
| LDL-C, mmol/L median IQR | 3.87 (2.83–5.08) | 2.90 (2.0–3.60) | <0.0001 |
| HDL-C, mmol/L median (IQR) | 1.22 (1.0–1.45) | 1.18 (1.0–1.5) | 0.41 |
| Triglycerides, mmol/L, median (IQR) | 1.25 (0.99-1.67) | 1.19 (0.9-1.60) | 0.18 |
| Creatinine, mmol/L, median (IQR) | 84 (62–106) | 77 (63–99) | 0.21 |
| TSH, pmol/L, median (IQR) | 3.4 (0.1–8.1) | 1.1 (0.8–1.8) | <0.04 |