Table 1.
Baseline Clinic features according to glycometabolism diagnosis by OGTT
| Clinic features | Diabetes mellitus (n = 1220) | Prediabetes (n = 777) | Normoglycemia (n = 910) | P |
|---|---|---|---|---|
| Age, y (median, Q1–3) | 64 (55, 73) | 61 (52,72) | 58 (49, 69)) | <0.001 |
| Male, n (%) | 711(58.3) | 501 (64.5%) | 616 (67.7) | <0.001 |
| Tobacco use, n (%) | 0.036 | |||
| Never | 712 (58.4) | 428 (55.1) | 480 (52.7) | |
| Quit | 110 (9.0) | 74 (9.5) | 79 (8.7) | |
| Current | 351 (28.8) | 246 (31.7) | 320 (35.2) | |
| Alcohol consumption, n (%) | 0.164 | |||
| Mild | 213 (17.5) | 132 (17.0) | 171 (18.8) | |
| Moderate to severe | 165 (13.5) | 131 (16.9) | 152 (16.7) | |
| Never | 817 (67.0) | 494 (63.6) | 564 (62.0) | |
| BMI, kg/m2 (median, Q1–3) | 25.0 (22.9,27.3) | 24.5 (22.5,26.8) | 24.2 (22.0,26.2) | <0.001 |
| NIHSS (median,Q1-Q3) | 5 (2–9) | 5 (2,9) | 4 (2–8) | 0.002 |
| Creatinine,m mol L−1 (median, Q1–3) | 71.2 (58.0, 87.0) | 72.0 (60.0, 87.0) | 71.8 (59.9, 86.7) | 0.425 |
| LDL, m mol L−1 (median, Q1–3) | 3.0 (2.4, 3.6) | 2.9 (2.3, 3.5) | 2.8 (2.3, 3.4) | 0.001 |
| HDL,m mol L−1(median, Q1–3) | 1.1(1.0, 1.3) | 1.2 (1.0, 1.4) | 1.2 (1.1, 1.4) | <0.001 |
| Systolic blood pressure, mmHg (median, Q1–3) | 150 (138, 160) | 143 (130, 160) | 146 (130, 160) | <0.001 |
| Homocysteine, μ mol L−1, (median, Q1–3) | 14.4 (11.5, 18.7) | 15.5 (12.0, 21.9) | 15.7 (12.3, 22.8) | <0.001 |
| HOMA2-IR (median, Q1–3) | 2.5 (1.6, 4.0) | 1.9 (1.1, 3.0) | 1.6 (0.9, 2.5) | <0.001 |
| Past medical history, yes, n (%) | ||||
| Coronary artery disease | 172 (14.1) | 87 (11.2) | 90 (9.9) | 0.009 |
| Hypertension | 795 (65.2) | 470 (60.5) | 514 (56.5) | <0.001 |
| Atrial fibrillation | 66 (5.4) | 54 (6.9) | 31 (3.4) | 0.006 |
| Stroke types, n (%) | <0.001 | |||
| IS | 1015 (83.2) | 541 (69.6) | 675 (74.2) | |
| ICH | 174 (14.3) | 185 (23.8) | 198 (21.8) | |
| SAH | 31 (2.5) | 51 (6.6) | 37 (4.1) |
OGTT the oral glucose tolerance test, BMI body mass index, LDL low density lipoprotein, HDL high density lipoprotein, NIHSS the National Institutes of Health Stroke Scale, HOMA2-IR the correctly solved computer model for homeostasis model assessment of insulin resistance, IS ischemic stroke, ICH intra-cerebral hemorrhage, SAH subarachnoid hemorrhage