Table 2.
Baseline Clinic features according to poor functional outcomes evaluated by mRS > 2
| Clinic features | Favorable outcomes (n = 1305) | Poor functional outcomes (n = 1602) | P |
|---|---|---|---|
| Age, y | 60 (52, 71) | 62 (53, 72) | 0.003 |
| Male, n (%) | 954 (73.1) | 1089 (68.0) | <0.001 |
| Tobacco use, n (%) | 0.036 | ||
| Never | 692 (53.0) | 928 (57.9) | |
| Quit | 126 (9.7) | 137 (8.6) | |
| Current | 436 (33.4) | 481 (30.0) | |
| Alcohol consumption, n (%) | 0.006 | ||
| Never | 811 (62.1) | 1064 (66.4) | |
| Mild | 266 (20.4) | 250 (15.6) | |
| Moderate to severe | 192 (14.7) | 256 (16.0) | |
| BMI(kg/m2) | 24.6 (22.5,26.7) | 24.5 (22.4,26.8) | 0.637 |
| NIHSS scales | <0.001 | ||
| <9 | 1256 (96.2) | 996 (62.2) | |
| 9–18 | 30 (2.3) | 474 (29.6) | |
| > 18 | 7 (0.5) | 124 (7.7) | |
| Creatinine (m mol L−1) | 72.7 (60.0, 87.5) | 70.0 (57.5,85.0) | 0.002 |
| LDL(m mol L−1) | 2.8 (2.3,3.5) | 2.9 (2.3,3.5) | 0.290 |
| HDL(m mol L−1) | 1.2 (1.0,1.4) | 1.2 (1.0,1.4) | 0.125 |
| Systolic blood pressure (mmHg) | 140 (130,160) | 150 (134,161) | <0.001 |
| Homocysteine (μmol L−1) | 14.6 (11.4,19.8) | 15.8 (12.3,21.4) | <0.001 |
| HOMA2-IR | 1.8 (1.1,3.0) | 2.0 (1.2,3.1) | 0.055 |
| Past medical history, yes, n (%) | |||
| Coronary heart disease | 146 (11.2) | 203 (12.7) | 0.230 |
| Hypertension | 785 (60.2) | 994 (62.0) | 0.296 |
| Atrial fibrillation | 53 (4.1) | 98 (6.1) | 0.013 |
| Stroke types, n (%) | <0.001 | ||
| Ischemic stroke | 1059 (81.1) | 1172 (73.2) | <0.001 |
| Cardioembolic | 44 (3.4) | 91 (5.7) | |
| Large-artery atherosclerosis | 565 (43.3) | 819 (51.1) | |
| Small-artery occlusion Lacunar | 367 (28.1) | 200 (12.5) | |
| Other demonstrated or undemonstrated | 38 (2.9) | 25 (1.6) | |
| ICH | 176 (13.5) | 381(23.8) | |
| SAH | 70 (5.4) | 49 (3.1) | |
| Glycometabolism status | <0.001 | ||
| Diabetes mellitus | 500 (38.3) | 720 (44.9) | |
| Prediabetes | 348 (26.7) | 429 (26.8) | |
| Normoglycaemia | 457 (35.0) | 453 (28.3) | |
mRS modified Rankin scale, BMI body mass index, LDL low density lipoprotein, HDL high density lipoprotein, NIHSS the National Institutes of Health Stroke Scale, HOMA2-IR the correctly solved computer model for homeostasis model assessment of insulin resistance, IS ischemic stroke, ICH intra-cerebral hemorrhage, SAH subarachnoid hemorrhage