Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Feb 1;36:19. doi: 10.1186/s40880-017-0186-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 3 — Id4 promoted proliferation and colony formation of HCC cells in vitro. The Cell Counting Kit-8 (CCK-8) assay was performed to examine cell proliferation. a, b Up-regulation of Id4 significantly promotes proliferation of SMMC-7721 and MHCC-97L cells. c, d Id4 knockdown significantly suppresses cell proliferation in Huh7 and PLC/PRF/5. e The number of colonies increased significantly in SMMC-7721-Id4 and MHCC-97L-Id4 groups. f The numbers of colonies decreased remarkably after Id4 silence in Huh7 and PLC/PRF/5groups. *P < 0.05, **P < 0.01, ***P < 0.001