Table 2.
Risk of VAP, duration of mechanical ventilation, length of stay and mortality in hospitalized patients in the ICU undergoing oral hygiene with chlorhexidine 0.12% oral solution (Control group) and toothbrushing with chlorhexidine gel 0.12% (Intervention group)
| Events | Control group (n = 108) | Intervention group (n = 105) | RR | CI(95%) | P value |
|---|---|---|---|---|---|
| VAP | |||||
| No | 80 (47,6%) | 88 (52,4%) | 1,0 | - | - |
| Yes | 28 (62,2%) | 17 (37,8%) | 1,81 | 0,93 – 3,57 | 0,084 |
| Death | |||||
| No | 81 (48,8%) | 85 (51,2%) | 1,0 | - | - |
| Yes | 27 (57,5%) | 20 (42,5%) | 1,41 | 0,73 – 2,70 | 0,296 |
| Duration of mechanical ventilationb | |||||
| Mean ± sd | 11,1 ± 7,6 | 8,7 ± 5,0 | 1,063 | 1,011 – 1,120 | 0,018a |
| Categorizationc | |||||
| Up to 5 days | 13 (37,1%) | 22 (62,9%) | 1,0 | - | - |
| 6 to 10 days | 40 (48,8%) | 42 (41,2%) | 1,61 | 0,71 – 3,70 | 0,249 |
| 11 days and more | 28 (57,1%) | 21 (42,9%) | 2,27 | 0,93 – 5,55 | 0,073 |
| Length of ICUb | |||||
| Mean ± sd | 13,9 ± 8,6 | 11,9 ± 7,77 | 1,032 | 0,999 – 1,065 | 0,064 |
| Categorizationd | |||||
| Up to 5 days | 11 (39,3%) | 17 (60,7%) | 1,0 | - | - |
| 6 to 10 days | 38 (50,0%) | 38 (50,0%) | 1,54 | 0,64 – 3,70 | 0,333 |
| 11 days and more | 59 (54,1%) | 50 (45,9%) | 1,82 | 0,78 – 4,34 | 0,164 |
astatistically significant association
bAmong patients who were discharged from the ICU (n = 166)
cChi-squared test for trend (χ 2 = 3,205; p = 0,073)
dChi-squared test for trend (χ 2 = 1,801; p = 0,179)