Table 2.
Clinical, parasitological and other parameters at enrolment in children with or without early rising asexual parasitaemia following artemisinin-based combination treatments
| Early rising asexual parasitaemia | P value | |||
|---|---|---|---|---|
| Yes (n = 205) | No (n = 211) | ALL (n = 416) | ||
| Gender (M/F [% female]) | 116/89 [43] | 117/94 [45] | 233/183 [44] | 0.89 |
| Age (year) | ||||
| Mean | 7.8 | 7.5 | 7.6 | 0.44 |
| 95% CI | 7.3–8.2 | 7.1–8 | 7.3–8 | |
| No. < 5 years | 36 | 48 | 84 | 0.23 |
| Duration of illness (day) | ||||
| Mean | 2.8 | 2.8 | 2.8 | 0.52 |
| 95% CI | 2.6–2.9 | 2.6–3 | 2.7–2.9 | |
| Temperature (°C) | ||||
| Mean | 38.3 | 38.1 | 38.2 | 0.51 |
| 95% CI | 38.1–38.5 | 37.9–38.3 | 38.1–32.7 | |
| No. ≥ 37.5 °C | 154 | 141 | 295 | 0.06 |
| No. ≥ 40 °C | 15 | 15 | 30 | 0.94 |
| Haematocrit (%) | ||||
| Mean | 32.1 | 32.4 | 32.3 | 0.43 |
| 95% CI | 31.5–32.7 | 31.8–33 | 31.8–32.7 | |
| No. <30% | 49 | 47 | 96 | 0.78 |
| Parasitaemia (μL−1) | ||||
| Geometric mean | 52,392 | 61,933 | 57,032 | 0.01 |
| Range | 2,220–536,912 | 1,800–1,096,636 | 1,800–1,096,636 | |
| No. ≥ 100,000 μL−1 | 40 | 85 | 125 | <0.0001 |
| No. ≥ 250,000 μL−1 | 12 | 24 | 36 | 0.045 |
CI confidence interval