Skip to main content
. 2017 Feb 1;18:10. doi: 10.1186/s12881-017-0372-0

Fig. 3.

Fig. 3

Analysis of renal function. a eGFR, calculated according to the CKD-EPI formula, in our BBS patients. The most severe renal dysfunction occurred in a patient carrying biallelic BBS10 mutations. b Relative eGFR decline in 3 years. eGFR was estimated at baseline (T0) and after 3 years (TIII). Relative eGFR change (ΔGFR) during 3 years is expressed as percentage (%) of the T0. c Urine albumin-to-creatinine ratio (ACR). Two of three mutated patients showed ACR above 30 mg/g; the other patient showed normal ACR. d Maximal urine concentrating ability. Urine osmolality was measured in the second morning urine void, after overnight fasting and water restriction