Table 2.
Univariate and multivariate logistic regression analyses to detect clinically significant prostate cancer
| Predictor | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| OR (95% CI) | p value | OR (95% CI) | p value | |
| Age | 1.040 (0.893–2.089) | 0.021 | 1.074 (1.008–1.243) | 0.031 |
| tPSA | 0.040 (0.012–0.089) | 0.238 | NA | |
| fPSA | 1.342 (0.712–1.993) | 0.413 | NA | |
| PSA f/t | 1.772 (0.832–2.116) | 0.043 | NA NA NA |
|
| MRI-based PV | 1.112 (1.069–1.157) | 0.011 | NA | |
| Adjusted PSAD | 6.433 (4.293–8.140) | <0.001 | 4.711 (3.704–6.313) | 0.013 |
| DRE results | 0.547 (0.199–1.639) | 0.078 | NA | |
| TRUS results | 0.961 (0.370–1.826) | 0.069 | NA | |
| PI-RADS v2 scores | 3.231 (2.173–6.804) | <0.001 | 2.171 (1.345–3.504) | <0.001 |
OR odds ratio, CI confidence interval, NA Not available, PSA Prostate-specific antigen, MRI Magnetic resonance imaging, PV Prostate volume, PSAD Prostate-specific antigen density, DRE Digital rectal examination, TRUS Transrectal ultrasound, PI-RADS v2 Prostate Imaging Reporting and Data System version 2