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. 2017 Jan 31;91(4):e01626-16. doi: 10.1128/JVI.01626-16

TABLE 2.

Sabaeus African green monkey candidate coreceptorsa

AGM Sab 7TMR % amino acid identity to 7TMR from:
No. of amino acids differing from human sequence
Human Rhesus macaque Sooty mangabey NTD ECL2
APJ 98.7 99.7 99.5 0 1
CCR2b 96.7 99.2 99.4 2 2
CCR3 93.5 98 97.2 6 4
CCR4 98.6 100 100 0 1
CCR5 97.4 99.1 98.9 2 1
CCR8 94.6 99.2 98.9 8 1
CXCR4 98.6 100 99.7 3 1
CXCR6 95.3 98.8 98.3 6 1
GPR1 98 100 99.7 1 1
GPR15 97.2 99.4 99.4 1 2
a

Seven-transmembrane receptors (7TMRs) were cloned from PBMC genomic DNA or cDNA, and the amino acid identity compared to human, rhesus macaque, and sooty mangabey molecules is shown. Also shown is the number of amino acids differing from the sequence of the human molecule in the N-terminal domain (NTD) and extracellular loop 2 (ECL2), which are implicated in coreceptor function based on studies with CCR5.