TABLE 2.

Comparison of nonsynonymous to synonymous nucleotide diversities by open reading frame from KRCV-1-infected crab-eating macaques^a

ORF	πN/πS	Mean πN ± SD	Mean πS ± SD	Significanceb
1a	0.59	0.00114 ± 0.000272	0.00194 ± 0.000688	****
1b	0.56	0.00116 ± 0.000341	0.00207 ± 0.000646	****
2a′	1.47	0.00263 ± 0.00141	0.00178 ± 0.00119	*
3′	0.58	0.00145 ± 0.000653	0.00249 ± 0.00188	*
4′	0.85	0.00223 ± 0.00108	0.00262 ± 0.00170	ns
2a	1.86	0.00258 ± 0.00243	0.00139 ± 0.000778	ns
2b	0.52	0.00102 ± 0.000444	0.00199 ± 0.00139	**
3	0.65	0.00100 ± 0.000347	0.00153 ± 0.000668	****
4	0.61	0.00123 ± 0.000414	0.00203 ± 0.00139	*
5a	0.56	0.00126 ± 0.000176	0.00224 ± 0.00136	**
5	0.70	0.00122 ± 0.000299	0.00176 ± 0.000614	***
6	0.53	0.00103 ± 0.000283	0.00196 ± 0.000538	****
7	1.03	0.00174 ± 0.000724	0.00169 ± 0.000492	ns

^aKRCV-1, Kibale red colobus virus 1; π, nucleotide diversity; ORF, open reading frame. Data for all time points and animals are combined for this analysis. ORFs with an πN/πS ratio of >1 are shown in bold.

^bSignificance values are as follows: *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001. ns, not significant.