TABLE 3.

Comparison of nonsynonymous to synonymous nucleotide diversities by open reading frame from SHFV-infected crab-eating macaques^a

ORF	πN/πSa	Mean πN ± SD	Mean πS ± SD	Significanceb
1a	0.59	0.00143 ± 0.000138	0.00242 ± 0.000326	****
1b	0.42	0.00115 ± 0.000118	0.00276 ± 0.000562	****
2a′	0.58	0.00153 ± 0.000591	0.00263 ± 0.00114	***
2b′	0.63	0.00142 ± 0.000243	0.00223 ± 0.000638	****
3′	0.53	0.00116 ± 0.000556	0.00221 ± 0.00101	****
4′	0.54	0.00140 ± 0.000463	0.00259 ± 0.00127	***
2a	0.40	0.00108 ± 0.000163	0.00271 ± 0.00116	****
2b	0.54	0.00124 ± 0.000349	0.00229 ± 0.000938	****
3	0.67	0.00128 ± 0.000255	0.00190 ± 0.000419	****
4	0.66	0.00122 ± 0.000286	0.00185 ± 0.000447	****
5a	1.05	0.00497 ± 0.00224	0.00474 ± 0.00376	ns
5	0.46	0.00136 ± 0.000308	0.00298 ± 0.00126	****
6	0.40	0.00127 ± 0.000197	0.00317 ± 0.00115	****
7	0.72	0.00211 ± 0.00137	0.00293 ± 0.001763	ns

^aORFs with an πN/πS ratio of >1 are shown in bold.

^bSignificance values are as follows: *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001. ns, not significant.