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Propofol inhibited the expression and activity of MMP-2, MMP-9 in EC9706. (A) Western blot analysis showed that propofol decreased the expression of MMP-2 and MMP-9, and increased the expression of TIMP-1 in a dose-dependent manner. (B) Gelatin zymography analysis showed that propofol inhibited the activity of MMP-2 and MMP-9 in a dose-dependent manner. # P<0.05 compared with control; * P<0.01 compared with control.
