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Extensive lymphoid infiltrates composed predominantly of T cells in a bone marrow with ALPS (case 9). (A) H&E, X 40 and X 500 (insert), (B) CD20, X 40, (C) CD3, X 40, (D) CD45RO, X 40, (E) CD4, X 40, (F) CD8, X 40. Note the markedly decreased expression of CD45RO in the T-cell infiltrates, consistent with the increase in DNT cells. The DNT cell population is less morphologically apparent using CD4 and CD8 staining.
