Table 2.
Chromosome Number | Medium 1991
|
RPMI 1640 with FUdR1
|
|||
---|---|---|---|---|---|
Fragile Sites2 | Expression of Fragile Sites (%) | Fragile Sites3 | Expression of Fragile Sites (%) | χ2 | |
1 | 24 | 8.0 | 87 | 7.8 | 0.00 |
2 | 18 | 6.0 | 104 | 9.3 | 2.92 |
3 | 81 | 26.9 | 232 | 20.8 | 4.88a |
4 | 9 | 3.0 | 47 | 4.2 | 0.63 |
5 | 15 | 5.0 | 70 | 6.3 | 0.48 |
6 | 12 | 4.0 | 98 | 8.8 | 6.92b |
7 | 18 | 6.0 | 85 | 7.6 | 0.70 |
8 | 8 | 2.7 | 31 | 2.8 | 0.01 |
9 | 11 | 3.6 | 35 | 3.1 | 0.07 |
10 | 13 | 4.3 | 30 | 2.7 | 1.64 |
11 | 10 | 3.3 | 31 | 2.8 | 0.10 |
12 | 8 | 2.7 | 28 | 2.5 | 0.00 |
13 | 6 | 2.0 | 18 | 1.6 | 0.04 |
14 | 6 | 2.0 | 31 | 2.8 | 0.30 |
15 | 3 | 1.0 | 16 | 1.4 | 0.09 |
16 | 42 | 14.0 | 86 | 7.7 | 10.58b |
17 | 2 | 0.7 | 14 | 1.2 | 0.30 |
18 | 5 | 1.7 | 22 | 2.0 | 0.01 |
19 | 0 | 0.0 | 9 | 0.8 | 1.33 |
20 | 1 | 0.3 | 7 | 0.6 | 0.03 |
21 | 0 | 0.0 | 5 | 0.4 | 0.38 |
22 | 1 | 0.3 | 5 | 0.4 | 0.05 |
X | 8 | 2.7 | 26 | 2.3 | 0.01 |
Y | 0 | 0.0 | 1 | 0.1 | 0.50 |
5,096 cells grown in Medium 199 were analyzed from 100 patients; 4,738 cells grown in RPMI with fluorodeoxyuridine (FUdR) were analyzed from 165 patients, χ2 is Chi-square.
Total fragile sites = 301.
Total fragile sites = 1,118.
P < 0.05.
P < 0.01, two-tailed test.