Table 3.
Chromosome Number | Medium 1991
|
RPMI 1640 with BrdU1
|
|||
---|---|---|---|---|---|
Fragile Sites2 | Expression of Fragile Sites (%) | Fragile Sites3 | Expression of Fragile Sites (%) | χ2 | |
1 | 27 | 8.1 | 25 | 4.1 | 6.02a |
2 | 21 | 6.3 | 40 | 6.6 | 0.00 |
3 | 90 | 27.1 | 41 | 6.7 | 73.32c |
4 | 10 | 3.0 | 56 | 9.2 | 11.54c |
5 | 15 | 4.5 | 48 | 7.9 | 3.31 |
6 | 13 | 3.9 | 29 | 4.8 | 0.18 |
7 | 22 | 6.6 | 32 | 5.2 | 0.54 |
8 | 9 | 2.7 | 17 | 2.8 | 0.02 |
9 | 11 | 3.3 | 55 | 9.0 | 9.80b |
10 | 14 | 4.2 | 55 | 9.0 | 6.54a |
11 | 10 | 3.0 | 20 | 3.3 | 0.00 |
12 | 8 | 2.4 | 41 | 6.7 | 7.20b |
13 | 6 | 1.8 | 17 | 2.8 | 0.49 |
14 | 7 | 2.1 | 27 | 4.4 | 2.66 |
15 | 3 | 0.9 | 4 | 0.7 | 0.00 |
16 | 48 | 14.5 | 64 | 10.5 | 2.92 |
17 | 2 | 0.6 | 8 | 1.3 | 0.46 |
18 | 6 | 1.8 | 7 | 1.2 | 0.30 |
19 | 0 | 0.0 | 3 | 0.5 | 0.45 |
20 | 1 | 0.3 | 0 | 0.0 | 0.10 |
21 | 0 | 0.0 | 0 | 0.0 | — |
22 | 1 | 0.3 | 1 | 0.2 | 0.09 |
X | 8 | 2.4 | 15 | 2.4 | 0.03 |
Y | 0 | 0.0 | 7 | 1.2 | 2.43 |
6,009 cells grown in Medium 199 were analyzed from 117 patients; 5,846 cells grown in RPMI with bromodeoxyuridine (BrdU) were analyzed from 121 patients, χ2 is Chi-square.
Total fragile sites = 332.
Total fragile sites = 612.
P < 0.05.
P < 0.01.
P < 0.001, two-tailed test.