Table 1. Cardiac catheterization and cardiopulmonary exercise test prior to and after cardiac surgery.

	Initial		After bosentan treatment		Post-operative
	At room air	After O2 (10 L/min) supply	At room air	After O2 (10 L/min) supply	At room air
Cardiac catheterization
Mean PA pressure (mmHg)	64	60	49	47	49
PVR (WU·m2)	13.9	8.3	10.2	6.0	6.4
Qp/Qs	1.2	2.0	1.7	2.0	1.9
SaO2 (%)	83	94	87	97	94
Cardiopulmonary exercise test
VO2 max (mL/kg/min)			20.4		23.9
Exercise duration (min)			4		6
SpO2 at rest (%)			84		92
SpO2 at peak exercise (%)			62		80

PA: pulmonary artery, PVR: pulmonary vascular resistance, WU: wood units, SaO₂: systemic arterial oxygen saturation, VO₂ max: maximal oxygen consumption, SpO₂: peripheral capillary oxygen saturation