Table 1. Drugs and drug doses used in the studies.

Treatment	Drug dose (mg kg−1)
Control Standard Regimen	INH	RIF	EMB	PZA
Standard Regimen	25	10	100	150
Enhanced Standard Regimen	25	10	100	450
Experimental TB Drug Regimens	CLZ	EMB	PRO	PZA
PRS Regimen I
H/L/L/H	25	11.1	8.3	450
H/L/H/L	25	11.1	75	50
H/H/L/L	25	100	8.3	50
H/H/H/H	25	100	75	450
H/H/H/L	25	100	75	50
H/H/L/H	25	100	8.3	450
H/L/H/H	25	11.1	75	450
H/H/M/M	25	100	25	150
H/M/H/M	25	33.3	75	150
H/M/M/H	25	33.3	25	450
	CLZ	EMB	BDQ	PZA
PRS Regimen II
H/L/L/H	25	11.1	5.6	450
H/L/H/L	25	11.1	50	50
H/H/L/L	25	100	5.6	50
H/H/H/H	25	100	50	450
H/H/H/L	25	100	50	50
H/H/L/H	25	100	5.6	450
H/L/H/H	25	11.1	50	450
H/H/M/M	25	100	16.7	150
H/M/H/M	25	33.3	50	150
H/M/M/H	25	33.3	16.7	450
PRS Regimen IIA	25	100	16.7	150
PRS Regimen IIB	25	100	16.7	450
PRS Regimen IIC	25	100	30	450