Table 2.
List of clinical trials which are combined use of promising candidates.
| Combine Use Candidate Vaccines | Current Status | Sponser | Start Date | Phase | Estimated Enrollments | Ages | Locations | ClinicalTrials.gov Identifier |
|---|---|---|---|---|---|---|---|---|
| Ad26-ZEBOV+MVA-BN Filo | Completed | Crucell Holland BV | Dec.2014 | 1 | 88 | 18-50 | UK | NCT02313077 |
| Ongoing | Crucell Holland BV | Jan.2015 | 1 | 164 | 18-50 | USA | NCT02325050 | |
| Ongoing | Crucell Holland BV | Apr.2015 | 1 | 78 | 18-50 | Uganda;Tanzania | NCT02376400 | |
| Ongoing | Crucell Holland BV | Mar.2015 | 1 | 72 | 18-50 | Ghana; Kenya | NCT02376426 | |
| Recruiting | Crucell Holland BV | Jun.2015 | 2 | 612 | 18-65 | France, UK | NCT02416453 | |
| Recruiting | Crucell Holland BV | Sept.2015 | 3 | 525 | 18-50 | USA | NCT02543567 | |
| Recruiting | Crucell Holland BV | Sept.2015 | 3 | 728 | 1-65 | Sierra Leone | NCT02509494 | |
| Recruiting | Crucell Holland BV | Oct.2015 | 2 | 1188 | 1-70 | Africa countries | NCT02564523 | |
| Ongoing | Crucell Holland BV | Sept.2015 | 3 | 329 | 18-50 | USA | NCT02543268 | |
| Recruiting | Crucell Holland BV | Jan.2016 | 2 | 575 | 18-70 | USA,Kenya,Nigeria | NCT02598388 | |
| Recruiting | Crucell Holland BV | Jan.2016 | 4 | 5500 | 1-71 | Not Provided | NCT02661464 | |
| Ad26.Filo+MVA-BN Filo | Not recruit | Janssen Vaccines & Prevention B.V. | Aug.2016 | 1 | 72 | 18-50 | USA | NCT02860650 |
| ChAd3-EBO-Z+MVA-BN Filo | Recruiting | University of Oxford | Dec.2014 | 1 | 92 | 18-50 | USA | NCT02240875 |
| Ongoing | University of Maryland | Nov.2014 | 1 | 91 | 18-50 | Mali | NCT02267109 | |
| ChAd3-EBO-Z+MVA-ZEBOV | Completed | University of Oxford | Jul.2015 | 1 | 40 | 18-50 | Senegal | NCT02485912 |
| Ongoing | University of Oxford | Apr.2015 | 1 | 38 | 18-50 | UK | NCT02451891 | |
| cAd3-EBO+MVA-ZEBOV | Ongoing | University of Maryland | May.2015 | 1 | 60 | 18-65 | Mali | NCT02368119 |
| Ongoing | NIAID | Mar.2015 | 1 | 64 | 18-66 | USA | NCT02408913 | |
| cAd3-EBO/ChAd3-EBO-Z+MVA-ZEBOV | Ongoing | NIAID | Jan.2015 | 1 | 90 | 18-65 | Uganda | NCT02354404 |
| ChAd3-EBO-Z+Ad26-ZEBOV | Ongoing | University of Oxford | Sept.2015 | 1 | 32 | 18-50 | UK | NCT02495246 |
| ChAd3-EBO-Z+rVSV-EBOV | Ongoing | NIAID | Jan.2015 | 2 | 28170 | 18+ | Liberia | NCT02344407 |
| ChAd3-EBO-Z+Nimenrix | Ongoing | GSK | Nov.2015 | 2 | 600 | 1-17 | Not Provided | NCT02548078 |
Abbreviations: NIAID = National Institute of Allergy and Infectious Diseases; GSK = GlaxoSmithKline; USA = United States; UK = United Kingdom.