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. 2016 Oct 21;13(1):220–228. doi: 10.1080/21645515.2016.1234553

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© 2017 GSK Biologicals SA. Published with license by Taylor & Francis.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 3. — Mouse survival upon pneumolysin intranasal challenge. Mice (n = 20/group) were immunized twice intramuscularly at a 2-week interval with 1 µg of dPly adjuvanted with alum or with alum only. Fourteen days after the second injection, mice were challenged intranasally with 2 µg of Ply. The mortality was recorded during 3 d.