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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: J Endocrinol. 2016 Oct 31;232(2):137–153. doi: 10.1530/JOE-16-0370

Figure 11.

Figure 11

Tubular aggregates (TAs) in sedentary Chga-KO GAS muscle. (A) Transverse section showing a large aggregate where sub-clusters display different tubule orientation relative to the sarcomere and mitochondria (MITO) in the outer border of TA. The inset shows a honeycomb-like TA. (B) Longitudinal section showing a TA, which runs parallel to the sarcomere. (C) Longitudinal section showing a TA with paracrystalline single-walled tubules of comparable area and a damaged mitochondrion (mitophagy). (D) Longitudinal section showing a TA, where paracrystalline tubules are of different areas. (E) Longitudinal section showing a TA with double-walled tubules and glycogen (GLY) granules in between two tubules. (F) Longitudinal section showing a TA where tubules are cut in the longitudinal, oblique or perpendicular to the sarcomere. Note triad and glycogen granules in the vicinity of TA. Black arrow points to T-tubule and white arrow points to smooth sarcoplasmic reticulum.