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. 2017 Feb 1;8(1):115–127. doi: 10.14336/AD.2016.0610

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Copyright: © 2017 Lin, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 3. — Number of CD34⁺, CD133⁺ and EPCs in the peripheral blood. (A) Number of circulating EPCs in mild and moderate traumatic brain injury (TBI) patients, showing a similar tendency of “from low to high”, peaked at 7 days and then gradually decreased and was significantly higher than that in the control group at 7 and 14 days after TBI (*p < 0.05). (B) Mild TBI patients were further divided into a good prognosis group (group A) and a poor prognosis group (group B). There was no significant difference in EPC number among group A, group B and moderate TBI group (P > 0.05). (C) CD34⁺ cell number in the peripheral blood of mild and moderate TBI patients was very high in the early stage after TBI and began to significantly decrease at 7 days after TBI, and was significantly higher than control group at 1, 4, 7 and 14 days after TBI (*p < 0.05). There was no significant difference in CD34⁺ cell number between mild and moderate TBI groups (p > 0.05). (D) CD133⁺ cell number in the peripheral blood of all TBI patients was also very high in the early stage after TBI and began to significantly decrease at 7 days after TBI, and was significantly higher than the control group at 1, 4, 7, 14 and 21 days after TBI (*p < 0.05). There was no significant difference in CD133⁺ cell number between mild and moderate TBI group (p > 0.05).