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. 2017 Feb 1;8(1):17–30. doi: 10.14336/AD.2016.1010

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Copyright: © 2017 Thangthaeng, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 3. — Effects of age and metformin on spatial memory. Effects of age and metformin treatment on spatial bias during the Morris water maze task, as measured by the percent time spent in an annulus 40-cm around the platform location. This probe trial during which the platform is not accessible is done on sessions 2,4,5,7 and 9 and on session 10 (7-day delay). Each value represents the mean ± SE of groups composed of 16-18 mice. The dotted line represents the % time spent in annulus 40cm due to chance.