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. 2017 Feb 1;12(2):e0171210. doi: 10.1371/journal.pone.0171210

Table 1. Basic data for all included studies in the meta-analysis.

First author Year Country Cohort sample size Cancer type (derived) Detection method HULC expression Survival quality score
Low/ high Low High Variance Analysis Outcomes
LNM DM Recurrence LNM DM Recurrence
Uzan VR, et al 2016 Brazil 33 Osteosarcoma (tissue) RT-PCR 21/12 NR NR NR NR NR NR Univariate OS, EFS 7
Yang Z, et al. 2015 Korea 240 Hepatocellular Carcinoma (tissue) RT-PCR NR NR NR NR NR NR NR Multivariateanalysis OS, DFS 7
Sun XH, et al. 2015 China 78 Osteosarcoma (tissue) RT-PCR 39/39 NR 5/34 NR NR 16/23 NR Multivariateanalysis OS 7
Li SP, et al. 2016 China 38 Hepatocellular Carcinoma (tissue) RT-PCR 15/23 NR 1/14 5/10 NR 8/15 16/7 Univariate OS 7
Jin C, et al. 2016 China 54 gastric cancer (serum) RT-PCR 27/27 25/27 2/50 NR 34/14 9/39 NR Univariate OS 7
Peng W, et al. 2014 China 304 pancreatic cancer (tissue) RT-PCR 92/212 23/69 NR 79/13 157/55 NR 208/4 Multivariateanalysis OS 8
Peng W, et al. 2016 China 142 Diffuse large B-cell lymphoma (lymph node) RT-PCR 47/95 NR NR NR NR NR NR Multivariateanalysis OS, PFS 8
Zhang Y, et al. 2016 China 42 gastric cancer (serum) RT-PCR 20/22 NR NR NR NR NR NR Univariate OS 8
Yang XJ, et al. 2016 China 35 colorectal carcinoma (tissue) RT-PCR 12/23 NR NR NR NR NR NR Univariate OS 8

Abbreviations: LNM, lymph node metastasis; DM, distant metastasis; OS, overall survival; DFS, disease-free survival; EFS, event-free survival; PFS, progression-free survival; NR, no report