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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Curr Dermatol Rep. 2016 Jul 13;5(3):179–190. doi: 10.1007/s13671-016-0154-5

Fig. 4.

Fig. 4

Methods of improving ALA-PDT by manipulating the light delivery parameters. Fractionated light delivery applies 20 % of the calculated red light dose after 4 h of ALA, incubation followed after 2 h by the remaining 80 % of the light dose. Daylight PDT involves exposing the patient to daylight for several hours as soon as the ALA has been applied. Wearable light sources allow a very low irradiance of red light to be applied for a longer time to reduce pain and make the treatment more patient friendly. iPDT uses an initial low dose of blue light exposure followed by red light to reduce the pain of treatment